The biceps femoris is unusual among skeletal muscles because its two heads are supplied by entirely different nerves: the long head is innervated by the tibial nerve, while the short head is innervated by the common fibular nerve. This dual innervation reflects the muscle's embryological split between two separate muscle masses that fused during development. Clinically, this means a nerve injury above the knee can knock out one head while leaving the other functional.
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