Swollen hands are a documented side effect of Rapamycin, flagged in a 2022 review by Gulayan on rapamycin's benefits and adverse effects. Peripheral edema of this kind is worth tracking for anyone using rapamycin off-label, since visible swelling is easy to self-monitor. It serves as a reminder that even drugs repurposed for longevity carry a real pharmacological side-effect profile.
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