Dairy Raises IGF-1 While Simultaneously Lowering Its Brake

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Higher dairy protein and calcium intake are 'highly significantly' associated not only with elevated IGF-1, but also with lower concentrations of IGFBP-2—the binding protein that normally limits IGF-1 bioavailability. Raising the signal while disabling its regulator is a double hit that amplifies effective growth-factor activity beyond what IGF-1 levels alone suggest.

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